Another Study Confirms Anti-Cancer Effects of THC and CBD

Jahan Marcu slide: Torres fig1

Another Study Confirms Anti-Cancer Effects of THC and CBDby – Jahan Marcu, Science EditorExcerpt below- read in full at Jahan’s blog: The Philadelphia Medical Marijuana Examiner

Last year, the journal of Molecular Cancer Therapeutics published research demonstrating that combination’s of THC and CBD, the two most abundant cannabinoids on the plant, can lead to a greater-than-additive or synergistic inhibition of cancer growth. Now, nearly a year to the date, the journal has published another article studying the anti-cancer effects of THC and CBD. The new article takes the next steps towards getting this therapy in to the clinic by testing THC and CBD in animals along side a common brain tumor drug TMZ (temozolomide).The study was conducted in Spain, and the experiments analyzing the effects of cannabinoids were conducted with tumors or brain cancer cells from human samples and a tumor xenograft mouse model. A tumor xenograft model is basically a cancer that is induced into an animal that has a compromised immune system. This allows researchers to give a mouse a tumor consisting of human cells, thus a promising anti-cancer treatment can be tested on a human tumor in a more natural environment, than a petri dish.The plant cannabinoids used for this study were “kindly provided by GW pharmaceuticals.” THC and CBD were also provided as plant extracts or “botanical drug substances,” meaning they contained small amounts of other cannabinoids. Allowing these researchers to construct a custom anti-cancer, Sativex-like substance. Other synthetic cannabinoids such as SR141716A and SR144528 were donated by Sonafi-Aventis.In the figure provided it shows that THC and TMZ can drastically inhibit the size of tumor. The pictures on the graph are of tumors after 15 days of treatment.

Read in full at Jahan’s blog: The Philadelphia Medical Marijuana Examiner

Attorney: Just Say No to Police

Bill Buckman at the PhillyNORML Freedom Forum 2009

William Buckman is a criminal defense attorney in New Jersey who recently published an excellent blog about how to handle police encounters:  Always Remain Silent… What To Do When Questioned By Police.  Bill is a prominent member of the national NORML Legal Committee and serves on the Board of Directors at NORML-NJ. The wisdom he shares is important reading for all cannabis consumers.

From In Bill’s Words March 2011 – I have practiced criminal law for over 30 years. I am still mystified as to why people under investigation speak to police. To try to help my clients I have placed on the back of my card the following:

My lawyer has told me not to talk to anyone about my case, not to answer questions, and not to reply to accusations. Call my lawyer if you want to ask me questions, search me or my property, do any tests, do any lineups, or any other identification procedures. I do not agree to any of these things without my lawyer present and I do not want to waive any of my constitutional rights. If I am being charged with DUI, I agree to a breath test.

Unfortunately too many people reach my office after they have spoken.

Let me be succinct: Of those of my clients convicted of an offense, 90% or more are convicted, at least partially, by something that came from their own mouths. The reasons clients give me for speaking are legion: “I just wanted to be cooperative; the police threatened me; I had nothing to hide;” etc.

Yet all excuses beg the question: Can you severely prejudice your case – guilty or innocent– if you speak to police. The answer is an emphatic “YES.”

I would note that a common misunderstanding among Americans is the fear that refusal to answer implies guilt. Whether this is true or not or what people may think of your decision to exercise your Fifth Amendment right (i.e. silence), should be dramatically overshadowed by the fact that what you consider a simple answer could land you in prison.

Read the full piece here, but the closing statement is worth emphasizing:

So if ever you are approached by police for “simple questioning”- please – JUST SAY NO or insist that your lawyer be present no matter how intimidating, threatening or even violent the encounter may be. It is far better to take abuse up front than to make a statement that can be used to hurt you for a much longer period of time.

Now that is some sound advice from one of America’s top lawyers for civil rights/criminal defense. Thank you Mr. Buckman!

Buckman Law Firm: http://www.whbuckman.com/

NORML Legal Committee: http://norml.org/index.cfm?Group_ID=3402

Don’t wait to get busted to help NORML legalize pot – make a donation today!

Chris Goldstein is a respected marijuana reform advocate. As a writer and radio broadcaster he has been covering cannabis news for over a decade. He volunteers with local groups to change prohibition laws including PhillyNORML and The Coalition for Medical Marijuana New Jersey. He enjoys old-school hip-hop, vintage airplanes and changing the world. Contact chris { at } freedomisgreen.com

10 Fast and Freewheeling Weed Quotes

Quotes are kinda like quick and easy snack food for the brain. Here’s some mental potato chips for your mind munching, thanks to the good folks at Baked Life.

1. “Even if one takes every reefer madness allegation of the prohibitionists at face value, marijuana prohibition has done far more harm to far more people than marijuana ever could.”- William F. Buckley Jr.

2. “Forty million Americans smoked marijuana; the only ones who didn’t like it were Judge Ginsberg, Clarence Thomas and Bill Clinton.” – Jay Leno

3. “I now have absolute proof that smoking even one marijuana cigarette is equal in brain damage to being on Bikini Island during an H-bomb blast” – Ronald Reagan

4. “The drug is really quite a remarkably safe one for humans, although it is really quite a dangerous one for mice and they should not use it.” – J.W.D Henderson Director of the Bureau of Human Drugs, Health and Welfare, Canada

5. “Casual drug users should be taken out and shot.” – Darryl Gates Head of Los Angeles Police Department, United States Senate Judiciary Committee

6. “When I was in England, I experimented with marijuana a time or two, and I didn’t like it. I didn’t inhale and never tried it again.” –Bill Clinton

7. “When I was a kid I inhaled frequently. That was the point.” – Barack Obama

8. “Now, like, I’m President. It would be pretty hard for some drug guy to come into the White House and start offering it up, you know? I bet if they did, I hope I would say, ‘Hey, get lost. We don’t want any of that.” – George W. Bush

9. “I think pot should be legal. I don’t smoke it, but I like the smell of it.” – Andy Warhol

10. “I used to smoke marijuana. But I’ll tell you something: I would only smoke it in the late evening. Oh, occasionally the early evening, but usually the late evening – or the mid-evening. Just the early evening, midevening and late evening. Occasionally, early afternoon, early midafternoon, or perhaps the late-midafternoon. Oh, sometimes the early-mid-late-early morning. . . . But never at dusk.” – Steve Martin


BONUS QUOTES!!!  BONUS QUOTES!!! BONUS QUOTES!!!  BONUS QUOTES!!!

“I used to do drugs. I still do, but I use to, too.” -Mitch Hedberg

“Some of my finest hours have been spent on my back veranda, smoking hemp and observing as far as my eye can see.” – Thomas Jefferson

Editor’s Note – The TJ quote was unattributed – LINK. The following however is fully attributed.

“Make the most of the Indian hemp seed, and sow it everywhere!”
George Washington in a note to his gardener at Mount Vernon (1794), The Writings of George Washington, Volume 33, page 270 (Library of Congress)